STC1 Antibody, Biotin conjugated (PACO32779)
- SKU:
- PACO32779
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | STC1 Antibody, Biotin conjugated (PACO32779) |
抗体コード: | PACO32779 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Stanniocalcin-1 protein (39-247AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia. |
シノニム: | Stanniocalcin-1 (STC-1), STC1, STC |
UniProt Protein Function: | STC1: Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia. Belongs to the stanniocalcin family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 8p21.2 Cellular Component: extracellular space; cytoplasm; apical plasma membrane; nucleus Molecular Function:hormone activity Biological Process: cellular calcium ion homeostasis; negative regulation of calcium ion transport; ossification; response to vitamin D; endothelial cell morphogenesis; decidualization; negative regulation of cell migration; embryo implantation |
NCBI Summary: | This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq, Jul 2008] |
UniProt Code: | P52823 |
NCBI GenInfo Identifier: | 1706175 |
NCBI Gene ID: | 6781 |
NCBI Accession: | P52823.1 |
UniProt Secondary Accession: | P52823,Q71UE5, |
UniProt Related Accession: | P52823 |
Molecular Weight: | |
NCBI Full Name: | Stanniocalcin-1 |
NCBI Synonym Full Names: | stanniocalcin 1 |
NCBI Official Symbol: | STC1 |
NCBI Official Synonym Symbols: | STC |
NCBI Protein Information: | stanniocalcin-1 |
UniProt Protein Name: | Stanniocalcin-1 |
Protein Family: | Stanniocalcin |
UniProt Gene Name: | STC1 |
UniProt Entry Name: | STC1_HUMAN |