STAM2 Antibody (PACO01546)
- SKU:
- PACO01546
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | STAM2 Antibody |
抗体コード: | PACO01546 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
反応性: | Human, Mouse |
免疫原: | synthesized peptide derived from human STAM2 around the non-phosphorylation site of Y192. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | STAM2; HBP; Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein |
UniProt Protein Function: | STAM2: an adaptor protein involved in the downstream signaling of cytokine receptors. Contain a SH3 domain and immunoreceptor tyrosine-based activation motif (ITAM). Acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. May modulate the signaling pathway downstream of JAK kinases upon cytokine stimulation. |
UniProt Protein Details: | Protein type:Adaptor/scaffold; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q23.3 Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; nucleoplasm Molecular Function:protein binding Biological Process: autophagy; endosome transport; negative regulation of epidermal growth factor receptor signaling pathway |
NCBI Summary: | The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008] |
UniProt Code: | O75886 |
NCBI GenInfo Identifier: | 71153548 |
NCBI Gene ID: | 10254 |
NCBI Accession: | O75886.1 |
UniProt Secondary Accession: | O75886,Q7LDQ0, Q9UF58, A8K8A0, D3DPA1, |
UniProt Related Accession: | O75886 |
Molecular Weight: | 38,370 Da |
NCBI Full Name: | Signal transducing adapter molecule 2 |
NCBI Synonym Full Names: | signal transducing adaptor molecule 2 |
NCBI Official Symbol: | STAM2 |
NCBI Official Synonym Symbols: | Hbp; STAM2A; STAM2B |
NCBI Protein Information: | signal transducing adapter molecule 2 |
UniProt Protein Name: | Signal transducing adapter molecule 2 |
UniProt Synonym Protein Names: | Hrs-binding protein |
Protein Family: | Signal transducing adapter molecule |
UniProt Gene Name: | STAM2 |
UniProt Entry Name: | STAM2_HUMAN |