ST14 Antibody (PACO01046)
- SKU:
- PACO01046
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ST14 Antibody |
抗体コード: | PACO01046 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | WB:1:500-1:2000, IF:1:200-1:1000 |
反応性: | Human |
免疫原: | synthesized peptide derived from the N-terminal region of human Matriptase. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | ST14; PRSS14; SNC19; TADG15; Suppressor of tumorigenicity 14 protein; Matriptase; Membrane-type serine protease 1; MT-SP1; Prostamin; Serine protease 14; Serine protease TADG-15; Tumor-associated differentially-expressed gene 15 protein |
UniProt Protein Function: | ST14: Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH). ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair. Belongs to the peptidase S1 family. |
UniProt Protein Details: | Protein type:EC 3.4.21.109; Membrane protein, integral; Protease Chromosomal Location of Human Ortholog: 11q24-q25 Cellular Component: extrinsic to plasma membrane; extracellular space; integral to plasma membrane; basolateral plasma membrane; plasma membrane Molecular Function:serine-type peptidase activity; serine-type endopeptidase activity Biological Process: keratinocyte differentiation; proteolysis Disease: Ichthyosis, Congenital, Autosomal Recessive 11 |
UniProt Code: | Q9Y5Y6 |
NCBI GenInfo Identifier: | 11415040 |
NCBI Gene ID: | 6768 |
NCBI Accession: | NP_068813 |
UniProt Secondary Accession: | Q9Y5Y6,Q9BS01, Q9H3S0, Q9HB36, Q9HCA3, |
UniProt Related Accession: | Q9Y5Y6 |
Molecular Weight: | 94,770 Da |
NCBI Full Name: | suppressor of tumorigenicity 14 protein |
NCBI Synonym Full Names: | suppression of tumorigenicity 14 (colon carcinoma) |
NCBI Official Symbol: | ST14 |
NCBI Official Synonym Symbols: | HAI; MTSP1; SNC19; ARCI11; MT-SP1; PRSS14; TADG15; TMPRSS14 |
NCBI Protein Information: | suppressor of tumorigenicity 14 protein; membrane-type serine protease 1; prostamin; serine protease 14; serine protease TADG-15; suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin); tumor associated differentially expressed gene 15 pr |
UniProt Protein Name: | Suppressor of tumorigenicity 14 protein |
UniProt Synonym Protein Names: | Matriptase; Membrane-type serine protease 1; MT-SP1; Prostamin; Serine protease 14; Serine protease TADG-15; Tumor-associated differentially-expressed gene 15 protein |
Protein Family: | Suppressor of tumorigenicity 14 protein |
UniProt Gene Name: | ST14 |
UniProt Entry Name: | ST14_HUMAN |