SSTR1 Antibody (PACO18926)
- SKU:
- PACO18926
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SSTR1 Antibody (PACO18926) |
抗体コード: | PACO18926 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human SSTR1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18926(SSTR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO18926(SSTR1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acid, . The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. |
シノニム: | somatostatin receptor 1 |
UniProt Protein Function: | SSTR1: Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins. Belongs to the G-protein coupled receptor 1 family. Interacts with SKB1. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 1; Cell cycle regulation; Receptor, GPCR; Membrane protein, integral Chromosomal Location of Human Ortholog: 14q13 Cellular Component: neuron projection; integral to plasma membrane; cytoplasm; plasma membrane Molecular Function:neuropeptide binding; somatostatin receptor activity Biological Process: response to starvation; G-protein signaling, coupled to cyclic nucleotide second messenger; negative regulation of cell proliferation; synaptic transmission; cell surface receptor linked signal transduction; cell-cell signaling; glutamate signaling pathway; neuropeptide signaling pathway; digestion; forebrain development; cerebellum development; spermatogenesis; response to nutrient |
NCBI Summary: | Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012] |
UniProt Code: | P30872 |
NCBI GenInfo Identifier: | 401124 |
NCBI Gene ID: | 6751 |
NCBI Accession: | P30872.1 |
UniProt Related Accession: | P30872 |
Molecular Weight: | Calculated MW: 42kDaObserved MW: 47kDa |
NCBI Full Name: | Somatostatin receptor type 1 |
NCBI Synonym Full Names: | somatostatin receptor 1 |
NCBI Official Symbol: | SSTR1 |
NCBI Official Synonym Symbols: | SS1R; SS1-R; SRIF-2; SS-1-R |
NCBI Protein Information: | somatostatin receptor type 1 |
UniProt Protein Name: | Somatostatin receptor type 1 |
UniProt Synonym Protein Names: | SRIF-2 |
Protein Family: | Somatostatin receptor |
UniProt Gene Name: | SSTR1 |
UniProt Entry Name: | SSR1_HUMAN |
Antibodies | ELISA Kits |
Anti-SSTR1 Antibody (CAB11659) | Human Somatostatin Receptor 1 ELISA Kit |
Anti-SSTR1 Antibody (CAB3134) | |
SSTR1 Antibody (PACO05133) | |
SSTR1 Antibody (PACO12481) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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