SPTBN2 Antibody (PACO12445)
- SKU:
- PACO12445
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SPTBN2 Antibody (PACO12445) |
抗体コード: | PACO12445 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human |
免疫原: | Human SPTBN2 |
憲法: | Liquid |
ストレージバッファ: | 0.1M NaHCO3,0.1M Glycine, 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | spectrin, beta, non-erythrocytic 2;SPTBN2;GTRAP41;SCA5 ; |
UniProt Protein Function: | Probably plays an important role in neuronal membrane skeleton. |
UniProt Protein Details: | |
NCBI Summary: | Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009] |
UniProt Code: | O15020 |
NCBI GenInfo Identifier: | 5902122 |
NCBI Gene ID: | 6712 |
NCBI Accession: | NP_008877.1 |
UniProt Secondary Accession: | O15020 |
UniProt Related Accession: | O15020 |
Molecular Weight: | 246kDa |
NCBI Full Name: | spectrin beta chain, non-erythrocytic 2 |
NCBI Synonym Full Names: | spectrin beta, non-erythrocytic 2 |
NCBI Official Symbol: | SPTBN2 |
NCBI Official Synonym Symbols: | SCA5; SCAR14; GTRAP41 |
NCBI Protein Information: | spectrin beta chain, non-erythrocytic 2 |
UniProt Protein Name: | Spectrin beta chain, non-erythrocytic 2 |
UniProt Synonym Protein Names: | Beta-III spectrin; Spinocerebellar ataxia 5 protein |
Protein Family: | Spectrin |
UniProt Gene Name: | SPTBN2 |
UniProt Entry Name: |