SOD3 Antibody, HRP conjugated (PACO30081)
- SKU:
- PACO30081
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | SOD3 Antibody, HRP conjugated (PACO30081) |
抗体コード: | PACO30081 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Extracellular superoxide dismutase [Cu-Zn] protein (19-160AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. |
シノニム: | Extracellular superoxide dismutase [Cu-Zn] (EC-SOD) (EC 1.15.1.1), SOD3 |
UniProt Protein Function: | SOD3: Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. Belongs to the Cu-Zn superoxide dismutase family. |
UniProt Protein Details: | Protein type:EC 1.15.1.1; Secreted, signal peptide; Oxidoreductase; Secreted Chromosomal Location of Human Ortholog: 4p15.2 Cellular Component: extracellular matrix; extracellular space; Golgi lumen; cytoplasm; extracellular region; trans-Golgi network; nucleus Molecular Function:heparin binding; protein binding; copper ion binding; zinc ion binding; superoxide dismutase activity Biological Process: response to reactive oxygen species; response to copper ion; removal of superoxide radicals; response to hypoxia |
NCBI Summary: | This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. [provided by RefSeq, Oct 2015] |
UniProt Code: | P08294 |
NCBI GenInfo Identifier: | 108885292 |
NCBI Gene ID: | 6649 |
NCBI Accession: | P08294.2 |
UniProt Related Accession: | P08294 |
Molecular Weight: | |
NCBI Full Name: | Extracellular superoxide dismutase |
NCBI Synonym Full Names: | superoxide dismutase 3 |
NCBI Official Symbol: | SOD3 |
NCBI Official Synonym Symbols: | EC-SOD |
NCBI Protein Information: | extracellular superoxide dismutase [Cu-Zn] |
UniProt Protein Name: | Extracellular superoxide dismutase [Cu-Zn] |
Protein Family: | Sodium channel |
UniProt Gene Name: | SOD3 |
UniProt Entry Name: | SODE_HUMAN |