SMYD3 Antibody (PACO17116)
- SKU:
- PACO17116
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SMYD3 Antibody (PACO17116) |
抗体コード: | PACO17116 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
反応性: | Human, Mouse |
免疫原: | Fusion protein of human SMYD3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17116(SMYD3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. |
シノニム: | SET and MYND domain containing 3 |
UniProt Protein Function: | SMYD3: Histone methyltransferase. Specifically methylates 'Lys- 4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. Belongs to the histone-lysine methyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.1.1.43; Methyltransferase, protein lysine; Methyltransferase Chromosomal Location of Human Ortholog: 1q44 Cellular Component: nucleoplasm; cytoplasm Molecular Function:metal ion binding; histone-lysine N-methyltransferase activity Biological Process: nucleosome assembly; establishment and/or maintenance of chromatin architecture; establishment of protein localization; myotube cell development; negative regulation of protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation |
NCBI Summary: | This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q9H7B4 |
NCBI GenInfo Identifier: | 212276523 |
NCBI Gene ID: | 64754 |
NCBI Accession: | Q9H7B4.4 |
UniProt Secondary Accession: | Q9H7B4,Q86TL8, Q8N5Z6, Q96AI5, A8K0P0, B1AN38, |
UniProt Related Accession: | Q9H7B4 |
Molecular Weight: | 428 |
NCBI Full Name: | Histone-lysine N-methyltransferase SMYD3 |
NCBI Synonym Full Names: | SET and MYND domain containing 3 |
NCBI Official Symbol: | SMYD3 |
NCBI Official Synonym Symbols: | KMT3E; ZMYND1; ZNFN3A1; bA74P14.1 |
NCBI Protein Information: | histone-lysine N-methyltransferase SMYD3; bA74P14.1 (novel protein); zinc finger, MYND domain containing 1; SET and MYND domain-containing protein 3; zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing) |
UniProt Protein Name: | Histone-lysine N-methyltransferase SMYD3 |
UniProt Synonym Protein Names: | SET and MYND domain-containing protein 3; Zinc finger MYND domain-containing protein 1 |
Protein Family: | Histone-lysine N-methyltransferase |
UniProt Gene Name: | SMYD3 |
UniProt Entry Name: | SMYD3_HUMAN |
Antibodies | ELISA Kits |
Anti-SMYD3 Antibody (CAB14516) | Human SMYD3 (SET and MYND domain containing 3) ELISA Kit (HUFI08451) |
Anti-SMYD3 Antibody (CAB7309) | |
SMYD3 Antibody (PACO12353) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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