SMOC1 Antibody, Biotin conjugated (PACO47105)
- SKU:
- PACO47105
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | SMOC1 Antibody, Biotin conjugated (PACO47105) |
抗体コード: | PACO47105 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human SPARC-related modular calcium-binding protein 1 protein (277-382AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Plays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation. |
シノニム: | SPARC-related modular calcium-binding protein 1 (Secreted modular calcium-binding protein 1) (SMOC-1), SMOC1 |
UniProt Protein Function: | SMOC1: Plays essential roles in both eye and limb development. Probale regulator of osteoblast differentiation. Defects in SMOC1 are the cause of ophthalmoacromelic syndrome (OAS). A rare disorder presenting with anophthalmia or microphthalmia and limb anomalies. Limb malformations include fused 4th and 5th metacarpals and short 5th finger in hands, and olygodactyly in foot (four toes). Most patients have bilateral anophthalmia/ microphthalmia, but unilateral abnormality is also noted. Other malformations are rare, but venous or vertebral anomaly was recognized each in single cases. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 14q24.2Molecular Function: protein bindingBiological Process: eye development; limb development; regulation of osteoblast differentiationDisease: Microphthalmia With Limb Anomalies |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
UniProt Code: | Q9H4F8 |
NCBI GenInfo Identifier: | 38258649 |
NCBI Gene ID: | 64093 |
NCBI Accession: | Q9H4F8.1 |
UniProt Secondary Accession: | Q9H4F8,Q96F78, A8K1S3, B2R7P5 |
UniProt Related Accession: | Q9H4F8 |
Molecular Weight: | 48,262 Da |
NCBI Full Name: | SPARC-related modular calcium-binding protein 1 |
NCBI Synonym Full Names: | SPARC related modular calcium binding 1 |
NCBI Official Symbol: | SMOC1 |
NCBI Official Synonym Symbols: | OAS |
NCBI Protein Information: | SPARC-related modular calcium-binding protein 1 |
UniProt Protein Name: | SPARC-related modular calcium-binding protein 1 |
UniProt Synonym Protein Names: | Secreted modular calcium-binding protein 1; SMOC-1 |
Protein Family: | SPARC-related modular calcium-binding protein |
UniProt Gene Name: | SMOC1 |
UniProt Entry Name: | SMOC1_HUMAN |