SMAD9 Antibody (PACO19299)
- SKU:
- PACO19299
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | SMAD9 Antibody (PACO19299) |
抗体コード: | PACO19299 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
反応性: | Human |
免疫原: | Synthetic peptide of human SMAD9 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19299(SMAD9 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-β family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene. |
シノニム: | SMAD family member 9 |
UniProt Protein Function: | Smad8: transcription factor phosphorylated and activated by bone morphogenetic protein receptor kinases. Phosphorylated Smads dimerize with collaborating Smad4 and are translocated into the nucleus, where they regulate transcription of target genes. Participates in a wide range of critical processes including morphogenesis, cell-fate determination, proliferation, differentiation and apoptosis. Two alternatively spliced products have been described. |
UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor; DNA-binding Chromosomal Location of Human Ortholog: 13q12-q14 Cellular Component: nucleoplasm; transcription factor complex; cytoplasm; intracellular; cytosol; nucleus Molecular Function:protein binding; DNA binding; metal ion binding; transcription factor activity; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Biological Process: BMP signaling pathway; Mullerian duct regression; transcription, DNA-dependent; ureteric bud development; positive regulation of transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; cartilage development; midbrain development; response to hypoxia; positive regulation of cell differentiation; protein amino acid phosphorylation; hindbrain development Disease: Pulmonary Hypertension, Primary, 2 |
NCBI Summary: | The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010] |
UniProt Code: | O15198 |
NCBI GenInfo Identifier: | 13959539 |
NCBI Gene ID: | 4093 |
NCBI Accession: | O15198.1 |
UniProt Secondary Accession: | O15198,O14989, Q5TBA1, A2A2Y6, |
UniProt Related Accession: | O15198 |
Molecular Weight: | 467 |
NCBI Full Name: | Mothers against decapentaplegic homolog 9 |
NCBI Synonym Full Names: | SMAD family member 9 |
NCBI Official Symbol: | SMAD9 |
NCBI Official Synonym Symbols: | PPH2; MADH6; MADH9; SMAD8; SMAD8A; SMAD8B |
NCBI Protein Information: | mothers against decapentaplegic homolog 9; MAD homolog 9; SMAD, mothers against DPP homolog 9; Mothers against decapentaplegic, drosophila, homolog of, 9 |
UniProt Protein Name: | Mothers against decapentaplegic homolog 9 |
UniProt Synonym Protein Names: | Madh6; SMAD family member 9; SMAD 9; Smad9 |
Protein Family: | Mothers against decapentaplegic |
UniProt Gene Name: | SMAD9 |
UniProt Entry Name: | SMAD9_HUMAN |