SLFN11 Antibody, HRP conjugated (PACO47675)
- SKU:
- PACO47675
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | SLFN11 Antibody, HRP conjugated (PACO47675) |
抗体コード: | PACO47675 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Schlafen family member 11 protein (670-821AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis. Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner. Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides. The exact inhibition mechanism is unclear: may either sequesters tRNAs, prevents their maturation via post-transcriptional processing or accelerates their deacylation. Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA. May play a role in cell cycle arrest and/or induction of apoptosis in response to exogenously induced DNA damage. |
シノニム: | Schlafen family member 11, SLFN11 |
UniProt Protein Function: | SLFN11: Belongs to the Schlafen family.Chromosomal Location of Human Ortholog: 17q12Cellular Component: nucleoplasm; cytoplasm; nucleusMolecular Function: ATP binding; tRNA bindingBiological Process: defense response to virus |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q7Z7L1 |
NCBI GenInfo Identifier: | 157388957 |
NCBI Gene ID: | 91607 |
NCBI Accession: | NP_001098057.1 |
UniProt Secondary Accession: | Q7Z7L1,Q8N3S8, Q8N762, Q8TEE0, E1P643 |
UniProt Related Accession: | Q7Z7L1 |
Molecular Weight: | 102,836 Da |
NCBI Full Name: | schlafen family member 11 |
NCBI Synonym Full Names: | schlafen family member 11 |
NCBI Official Symbol: | SLFN11 |
NCBI Official Synonym Symbols: | SLFN8/9 |
NCBI Protein Information: | schlafen family member 11 |
UniProt Protein Name: | Schlafen family member 11 |
UniProt Synonym Protein Names: | |
Protein Family: | Schlafen family |
UniProt Gene Name: | SLFN11 |
UniProt Entry Name: | SLN11_HUMAN |