SLCO1A2 Antibody, HRP conjugated (PACO58914)
- SKU:
- PACO58914
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | SLCO1A2 Antibody, HRP conjugated (PACO58914) |
抗体コード: | PACO58914 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Solute carrier organic anion transporter family member 1A2 protein (406-513AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acid, (By similarity). Selectively inhibited by the grapefruit juice component naringin. |
シノニム: | Solute carrier organic anion transporter family member 1A2 (OATP-A) (Organic anion-transporting polypeptide 1) (OATP-1) (Sodium-independent organic anion transporter) (Solute carrier family 21 member 3), SLCO1A2, OATP OATP1 OATP1A2 SLC21A3 |
UniProt Protein Function: | SLCO1A2: Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids. Selectively inhibited by the grapefruit juice component naringin. Belongs to the organo anion transporter (TC 2.A.60) family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter Chromosomal Location of Human Ortholog: 12p12 Cellular Component: integral to membrane; plasma membrane Molecular Function:organic anion transmembrane transporter activity Biological Process: bile acid and bile salt transport; sodium-independent organic anion transport; bile acid metabolic process; transmembrane transport; organic anion transport |
NCBI Summary: | This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008] |
UniProt Code: | P46721 |
NCBI GenInfo Identifier: | 10835099 |
NCBI Gene ID: | 6579 |
NCBI Accession: | NP_066580.1 |
UniProt Secondary Accession: | P46721,Q9UGP7, Q9UL38, |
UniProt Related Accession: | P46721 |
Molecular Weight: | 74,145 Da |
NCBI Full Name: | solute carrier organic anion transporter family member 1A2 |
NCBI Synonym Full Names: | solute carrier organic anion transporter family, member 1A2 |
NCBI Official Symbol: | SLCO1A2 |
NCBI Official Synonym Symbols: | OATP; OATP-A; OATP1A2; SLC21A3 |
NCBI Protein Information: | solute carrier organic anion transporter family member 1A2; OATP-1; solute carrier family 21 member 3; organic anion transporting polypeptide A; organic anion-transporting polypeptide 1; sodium-independent organic anion transporter; solute carrier family |
UniProt Protein Name: | Solute carrier organic anion transporter family member 1A2 |
UniProt Synonym Protein Names: | OATP-A; Organic anion-transporting polypeptide 1; OATP-1; Sodium-independent organic anion transporter; Solute carrier family 21 member 3 |
UniProt Gene Name: | SLCO1A2 |
UniProt Entry Name: | SO1A2_HUMAN |