SLC9A3R2 Antibody (PACO49026)
- SKU:
- PACO49026
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SLC9A3R2 Antibody (PACO49026) |
抗体コード: | PACO49026 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Na(+)/H(+) exchange regulatory cofactor NHE-RF2 protein (106-313AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: A549 whole cell lysate, MCF-7 whole cell lysate, PC-3 whole cell lysate. All lanes: SLC9A3R2 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 38, 37, 25 kDa. Observed band size: 38 kDa.. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO49026 at dilution of 1:100. |
バックグラウンド: | Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus. |
シノニム: | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1), SLC9A3R2, NHERF2 |
UniProt Protein Function: | Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3 (PubMed:18829453). May also act as scaffold protein in the nucleus. |
NCBI Summary: | This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q15599 |
NCBI GenInfo Identifier: | 194018553 |
NCBI Gene ID: | 9351 |
NCBI Accession: | NP_001123484.1 |
UniProt Secondary Accession: | Q15599,O00272, O00556, Q3KQY7, D3DU84, D3DU85, H3BSV6 |
UniProt Related Accession: | Q15599 |
Molecular Weight: | 24,718 Da |
NCBI Full Name: | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform a |
NCBI Synonym Full Names: | SLC9A3 regulator 2 |
NCBI Official Symbol: | SLC9A3R2 |
NCBI Official Synonym Symbols: | SIP1; OCTS2; SIP-1; TKA-1; E3KARP; NHERF2; NHE3RF2; NHERF-2 |
NCBI Protein Information: | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 |
UniProt Protein Name: | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 |
UniProt Synonym Protein Names: | NHE3 kinase A regulatory protein E3KARP; SRY-interacting protein 1; SIP-1; Sodium-hydrogen exchanger regulatory factor 2; Solute carrier family 9 isoform A3 regulatory factor 2; Tyrosine kinase activator protein 1; TKA-1 |
UniProt Gene Name: | SLC9A3R2 |