SLC6A15 Antibody (PACO41326)
- SKU:
- PACO41326
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SLC6A15 Antibody (PACO41326) |
抗体コード: | PACO41326 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Sodium-dependent neutral amino acid, transporter B(0)AT2 protein (357-452AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human bladder cancer using PACO41326 at dilution of 1:100. | |
Immunofluorescent analysis of HepG2 cells using PACO41326 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO41326 at dilution of 1:100. |
バックグラウンド: | Functions as a sodium-dependent neutral amino acid, transporter. Exhibits preference for the branched-chain amino acid, , particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent. |
シノニム: | Sodium-dependent neutral amino acid, transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Sodium-coupled branched-chain amino-acid, transporter 1) (Solute carrier family 6 member 15) (Transporter v7-3), SLC6A15, B0AT2 NTT73 SBAT1 |
UniProt Protein Function: | SLC6A15: Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 12q21.31 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:amino acid transmembrane transporter activity; proline:sodium symporter activity Biological Process: amino acid transport; leucine transport; neutral amino acid transport; proline transport |
NCBI Summary: | This gene encodes a member of the solute carrier family 6 protein family which transports neutral amino acids. The encoded protein is thought to play a role in neuronal amino acid transport (PMID: 16185194) and may be associated with major depression (PMID: 21521612). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] |
UniProt Code: | Q9H2J7 |
NCBI GenInfo Identifier: | 18202939 |
NCBI Gene ID: | 55117 |
NCBI Accession: | Q9H2J7.1 |
UniProt Secondary Accession: | Q9H2J7,Q9H9F5, A8K592, B7Z2P7, E7ESJ5, |
UniProt Related Accession: | Q9H2J7 |
Molecular Weight: | 82kDa |
NCBI Full Name: | Sodium-dependent neutral amino acid transporter B(0)AT2 |
NCBI Synonym Full Names: | solute carrier family 6 member 15 |
NCBI Official Symbol: | SLC6A15 |
NCBI Official Synonym Symbols: | V7-3; NTT73; SBAT1; hv7-3 |
NCBI Protein Information: | sodium-dependent neutral amino acid transporter B(0)AT2 |
UniProt Protein Name: | Sodium-dependent neutral amino acid transporter B(0)AT2 |
UniProt Synonym Protein Names: | Sodium- and chloride-dependent neurotransmitter transporter NTT73; Sodium-coupled branched-chain amino-acid transporter 1; Solute carrier family 6 member 15; Transporter v7-3 |
UniProt Gene Name: | SLC6A15 |