SLC25A1 Antibody (PACO17104)
- SKU:
- PACO17104
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SLC25A1 Antibody (PACO17104) |
抗体コード: | PACO17104 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human SLC25A1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17104(SLC25A1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17104(SLC25A1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | This gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate small metabolites across the mitochondrial membrane. This protein regulates the movement of citrate across the inner membranes of the mitochondria. Mutations in this gene have been associated with combined D-2- and L-2-hydroxyglutaric acid, ria. |
シノニム: | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 |
UniProt Protein Function: | SLC25A1: Involved in citrate-H(+)/malate exchange. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Belongs to the mitochondrial carrier family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 22q11.21 Cellular Component: integral to membrane; mitochondrial inner membrane; nucleus Molecular Function:citrate transmembrane transporter activity; tricarboxylic acid transmembrane transporter activity Biological Process: gluconeogenesis; mitochondrial citrate transport Disease: Combined D-2- And L-2-hydroxyglutaric Aciduria |
NCBI Summary: | This gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate small metabolites across the mitochondrial membrane. This protein regulates the movement of citrate across the inner membranes of the mitochondria. Mutations in this gene have been associated with combined D-2- and L-2-hydroxyglutaric aciduria. Pseudogenes of this gene have been identified on chromosomes 7, 11, 16, and 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
UniProt Code: | P53007 |
NCBI GenInfo Identifier: | 20141931 |
NCBI Gene ID: | 6576 |
NCBI Accession: | P53007.2 |
UniProt Secondary Accession: | P53007,Q9BSK6, A8K8E8, |
UniProt Related Accession: | P53007 |
Molecular Weight: | 34kDa |
NCBI Full Name: | Tricarboxylate transport protein, mitochondrial |
NCBI Synonym Full Names: | solute carrier family 25 member 1 |
NCBI Official Symbol: | SLC25A1 |
NCBI Official Synonym Symbols: | CTP; SEA; D2L2AD; SLC20A3 |
NCBI Protein Information: | tricarboxylate transport protein, mitochondrial |
UniProt Protein Name: | Tricarboxylate transport protein, mitochondrial |
UniProt Synonym Protein Names: | Citrate transport protein; CTP; Solute carrier family 25 member 1; Tricarboxylate carrier protein |
UniProt Gene Name: | SLC25A1 |