SIRPB1 Antibody, HRP conjugated (PACO59134)
- SKU:
- PACO59134
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | SIRPB1 Antibody, HRP conjugated (PACO59134) |
抗体コード: | PACO59134 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Signal-regulatory protein beta-1 isoform 3 protein (30-206AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. |
シノニム: | Signal-regulatory protein beta-1 isoform 3 (SIRP-beta-1 isoform 3), SIRPB1 |
UniProt Protein Function: | SIRPB1 iso3: Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 20p13Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: protein bindingBiological Process: cell surface receptor linked signal transduction; innate immune response; signal transduction |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009] |
UniProt Code: | Q5TFQ8 |
NCBI GenInfo Identifier: | 205829937 |
NCBI Gene ID: | 10326 |
NCBI Accession: | Q5TFQ8.1 |
UniProt Secondary Accession: | Q5TFQ8,Q7Z3B9 |
UniProt Related Accession: | Q5TFQ8, O00241 |
Molecular Weight: | 43,211 Da |
NCBI Full Name: | Signal-regulatory protein beta-1 isoform 3 |
NCBI Synonym Full Names: | signal regulatory protein beta 1 |
NCBI Official Symbol: | SIRPB1 |
NCBI Official Synonym Symbols: | CD172b; SIRP-BETA-1 |
NCBI Protein Information: | signal-regulatory protein beta-1 |
UniProt Protein Name: | Signal-regulatory protein beta-1 isoform 3 |
UniProt Synonym Protein Names: | |
Protein Family: | Signal-regulatory protein |
UniProt Gene Name: | SIRPB1 |
UniProt Entry Name: | SIRBL_HUMAN |