SIPA1 Antibody (PACO18918)
- SKU:
- PACO18918
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SIPA1 Antibody (PACO18918) |
抗体コード: | PACO18918 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Synthetic peptide of human SIPA1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18918(SIPA1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18918(SIPA1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. |
シノニム: | signal-induced proliferation-associated 1 |
UniProt Protein Function: | SIPA1: GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting it to the putatively inactive GDP-bound state. |
UniProt Protein Details: | Protein type:GAPs; GAPs, Ras Chromosomal Location of Human Ortholog: 11q13 Cellular Component: cytosol; nucleus Molecular Function:GTPase activator activity; protein binding Biological Process: cell proliferation; signal transduction |
NCBI Summary: | The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96FS4 |
NCBI GenInfo Identifier: | 20455286 |
NCBI Gene ID: | 6494 |
NCBI Accession: | Q96FS4.1 |
UniProt Secondary Accession: | Q96FS4,O14518, O60484, O60618, Q2YD83, |
UniProt Related Accession: | Q96FS4 |
Molecular Weight: | 112,149 Da |
NCBI Full Name: | Signal-induced proliferation-associated protein 1 |
NCBI Synonym Full Names: | signal-induced proliferation-associated 1 |
NCBI Official Symbol: | SIPA1 |
NCBI Official Synonym Symbols: | SPA1 |
NCBI Protein Information: | signal-induced proliferation-associated protein 1 |
UniProt Protein Name: | Signal-induced proliferation-associated protein 1 |
UniProt Synonym Protein Names: | GTPase-activating protein Spa-1; p130 SPA-1 |
Protein Family: | Signal-induced proliferation-associated protein |
UniProt Gene Name: | SIPA1 |
UniProt Entry Name: | SIPA1_HUMAN |
Antibodies |
Anti-SIPA1 Antibody (CAB12253) |
Anti-SIPA1 Antibody (CAB19867)[KO Validated] |
SIPA1 Antibody (PACO12215) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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