SGCG Antibody, HRP conjugated (PACO60009)
- SKU:
- PACO60009
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | SGCG Antibody, HRP conjugated (PACO60009) |
抗体コード: | PACO60009 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Gamma-sarcoglycan protein (108-221AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. |
シノニム: | Gamma-sarcoglycan (Gamma-SG) (35 kDa dystrophin-associated glycoprotein) (35DAG), SGCG |
UniProt Protein Function: | SGCG: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCG are the cause of limb-girdle muscular dystrophy type 2C (LGMD2C). LGMD2C is characterized by progressive muscle wasting from early childhood. Belongs to the sarcoglycan beta/delta/gamma/zeta family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Dystrophin complex Chromosomal Location of Human Ortholog: 13q12 Cellular Component: cytoskeleton; cytoplasm; plasma membrane; integral to membrane; sarcoglycan complex; sarcolemma Molecular Function:protein binding Biological Process: cardiac muscle development; muscle development; heart contraction; muscle cell development Disease: Muscular Dystrophy, Limb-girdle, Type 2c |
NCBI Summary: | This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008] |
UniProt Code: | Q13326 |
NCBI GenInfo Identifier: | 313104319 |
NCBI Gene ID: | 6445 |
NCBI Accession: | Q13326.4 |
UniProt Secondary Accession: | Q13326,Q32M32, Q5T9J6, |
UniProt Related Accession: | Q13326 |
Molecular Weight: | 291 |
NCBI Full Name: | Gamma-sarcoglycan |
NCBI Synonym Full Names: | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
NCBI Official Symbol: | SGCG |
NCBI Official Synonym Symbols: | A4; MAM; DMDA; SCG3; TYPE; DAGA4; DMDA1; LGMD2C; SCARMD2 |
NCBI Protein Information: | gamma-sarcoglycan; 35DAG; gamma-SG; gamma sarcoglycan; 35kD dystrophin-associated glycoprotein; 35 kDa dystrophin-associated glycoprotein |
UniProt Protein Name: | Gamma-sarcoglycan |
UniProt Synonym Protein Names: | 35 kDa dystrophin-associated glycoprotein; 35DAG |
Protein Family: | Gamma-sarcoglycan |
UniProt Gene Name: | SGCG |
UniProt Entry Name: | SGCG_HUMAN |