SGCB Antibody, HRP conjugated (PACO59050)
- SKU:
- PACO59050
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | SGCB Antibody, HRP conjugated (PACO59050) |
抗体コード: | PACO59050 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Beta-sarcoglycan protein (124-219AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. |
シノニム: | Beta-sarcoglycan (Beta-SG) (43 kDa dystrophin-associated glycoprotein) (43DAG) (A3b), SGCB |
UniProt Protein Function: | SGCB: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCB are the cause of limb-girdle muscular dystrophy type 2E (LGMD2E). LGMD2E is an autosomal recessive disorder. Belongs to the sarcoglycan beta/delta/gamma/zeta family. |
UniProt Protein Details: | Protein type:Dystrophin complex; Membrane protein, integral Chromosomal Location of Human Ortholog: 4q12 Cellular Component: dystrophin-associated glycoprotein complex; cytoskeleton; integral to plasma membrane; cytoplasm; sarcoglycan complex; sarcolemma Biological Process: muscle development; cardiac muscle cell development; muscle fiber development Disease: Muscular Dystrophy, Limb-girdle, Type 2e |
NCBI Summary: | This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.[provided by RefSeq, Oct 2008] |
UniProt Code: | Q16585 |
NCBI GenInfo Identifier: | 13431857 |
NCBI Gene ID: | 6443 |
NCBI Accession: | Q16585.1 |
UniProt Secondary Accession: | Q16585,O00661, B7Z635, |
UniProt Related Accession: | Q16585 |
Molecular Weight: | 318 |
NCBI Full Name: | Beta-sarcoglycan |
NCBI Synonym Full Names: | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
NCBI Official Symbol: | SGCB |
NCBI Official Synonym Symbols: | A3b; SGC; LGMD2E |
NCBI Protein Information: | beta-sarcoglycan; 43DAG; beta-SG; 43 kDa dystrophin-associated glycoprotein; limb girdle muscular dystrophy 2E (non-linked families); beta-sarcoglycan(43kD dystrophin-associated glycoprotein) |
UniProt Protein Name: | Beta-sarcoglycan |
UniProt Synonym Protein Names: | 43 kDa dystrophin-associated glycoprotein; 43DAG; A3b |
Protein Family: | Beta-sarcoglycan |
UniProt Gene Name: | SGCB |
UniProt Entry Name: | SGCB_HUMAN |