SETD3 Antibody, HRP conjugated (PACO58229)
- SKU:
- PACO58229
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | SETD3 Antibody, HRP conjugated (PACO58229) |
抗体コード: | PACO58229 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Histone-lysine N-methyltransferase setd3 protein (166-265AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3 (H3K4me and H3K36me). Acts as a transcriptional activator. Plays an important role in the transcriptional regulation of muscle cell differentiation via interaction with MYOD1. |
シノニム: | Histone-lysine N-methyltransferase setd3 (EC 2.1.1.43) (SET domain-containing protein 3), SETD3, C14orf154 |
UniProt Protein Function: | SETD3: Histone methyltransferase that methylates 'Lys-36' of histone H3 (H3K36me). H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. Belongs to the SETD3 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Methyltransferase, protein lysine; EC 2.1.1.43; Methyltransferase Chromosomal Location of Human Ortholog: 14q32.2 Cellular Component: nuclear chromatin Molecular Function:histone lysine N-methyltransferase activity (H3-K4 specific); transcription coactivator activity; histone lysine N-methyltransferase activity (H3-K36 specific) Biological Process: transcription, DNA-dependent; peptidyl-lysine di-methylation; positive regulation of transcription, DNA-dependent; peptidyl-lysine tri-methylation; histone H3-K4 methylation; peptidyl-lysine mono-methylation; positive regulation of muscle cell differentiation; histone H3-K36 methylation; positive regulation of transcription from RNA polymerase II promoter |
UniProt Code: | Q86TU7 |
NCBI GenInfo Identifier: | 40068481 |
NCBI Gene ID: | 84193 |
NCBI Accession: | NP_115609.2 |
UniProt Secondary Accession: | Q86TU7,Q0VAQ2, Q659C0, Q86TU8, Q96GY9, Q9H5U5, A0PJU3 A5PLP0, B4DZE8, |
UniProt Related Accession: | Q86TU7 |
Molecular Weight: | 67kDa |
NCBI Full Name: | histone-lysine N-methyltransferase setd3 isoform a |
NCBI Synonym Full Names: | SET domain containing 3 |
NCBI Official Symbol: | SETD3 |
NCBI Official Synonym Symbols: | C14orf154 |
NCBI Protein Information: | histone-lysine N-methyltransferase setd3 |
UniProt Protein Name: | Histone-lysine N-methyltransferase setd3 |
UniProt Synonym Protein Names: | SET domain-containing protein 3 |
Protein Family: | Histone-lysine N-methyltransferase |
UniProt Gene Name: | SETD3 |
UniProt Entry Name: | SETD3_HUMAN |