SERPINB9 Antibody (PACO43377)
- SKU:
- PACO43377
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SERPINB9 Antibody (PACO43377) |
抗体コード: | PACO43377 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
反応性: | Human |
免疫原: | Recombinant Human Serpin B9 protein (1-376AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: Serpin B9 antibody at 3µg/ml + K562 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 42 kDa. Observed band size: 42 kDa. |
バックグラウンド: | Granzyme B inhibitor. |
シノニム: | Serpin B9 (Cytoplasmic antiproteinase 3) (CAP-3) (CAP3) (Peptidase inhibitor 9) (PI-9), SERPINB9, PI9 |
UniProt Protein Function: | SERPINB9: Granzyme B inhibitor. Belongs to the serpin family. Ov-serpin subfamily. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 6p25 Cellular Component: extracellular space; membrane; cytoplasm; intracellular; nucleus; cytosol Molecular Function:serine-type endopeptidase inhibitor activity; protein binding; protease binding; caspase inhibitor activity Biological Process: mast cell mediated immunity; response to bacterium; immune response; negative regulation of caspase activity; negative regulation by symbiont of host apoptosis; protection from natural killer cell mediated cytotoxicity; negative regulation of apoptosis |
NCBI Summary: | This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012] |
UniProt Code: | P50453 |
NCBI GenInfo Identifier: | 1709896 |
NCBI Gene ID: | 5272 |
NCBI Accession: | P50453.1 |
UniProt Secondary Accession: | P50453,Q5TD03, B2RBW3, |
UniProt Related Accession: | P50453 |
Molecular Weight: | 376 |
NCBI Full Name: | Serpin B9 |
NCBI Synonym Full Names: | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
NCBI Official Symbol: | SERPINB9 |
NCBI Official Synonym Symbols: | PI9; CAP3; PI-9; CAP-3 |
NCBI Protein Information: | serpin B9; peptidase inhibitor 9; cytoplasmic antiproteinase 3; protease inhibitor 9 (ovalbumin type); serpin peptidase inhibitor, clade B, member 9; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9 |
UniProt Protein Name: | Serpin B9 |
UniProt Synonym Protein Names: | Cytoplasmic antiproteinase 3; CAP-3; CAP3; Peptidase inhibitor 9; PI-9 |
Protein Family: | Serpin |
UniProt Gene Name: | SERPINB9 |
UniProt Entry Name: | SPB9_HUMAN |