SERPINB8 Antibody, Biotin conjugated (PACO29847)
- SKU:
- PACO29847
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | SERPINB8 Antibody, Biotin conjugated (PACO29847) |
抗体コード: | PACO29847 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Serpin B8 protein (60-242AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
シノニム: | Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Peptidase inhibitor 8) (PI-8), SERPINB8, PI8 |
UniProt Protein Function: | SERPINB8: Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing |
UniProt Protein Details: | Protein type:Inhibitor Chromosomal Location of Human Ortholog: 18q22.1 Cellular Component: extracellular space; cytosol Molecular Function:serine-type endopeptidase inhibitor activity; protein binding |
NCBI Summary: | The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).[supplied by OMIM, Jan 2010] |
UniProt Code: | P50452 |
NCBI GenInfo Identifier: | 73623033 |
NCBI Gene ID: | 5271 |
NCBI Accession: | NP_001027018.1 |
UniProt Secondary Accession: | P50452,Q7Z2V6, Q8N178, B4DTW2, |
UniProt Related Accession: | P50452 |
Molecular Weight: | 22,134 Da |
NCBI Full Name: | serpin B8 isoform b |
NCBI Synonym Full Names: | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
NCBI Official Symbol: | SERPINB8 |
NCBI Official Synonym Symbols: | PI8; CAP2 |
NCBI Protein Information: | serpin B8 |
UniProt Protein Name: | Serpin B8 |
UniProt Synonym Protein Names: | Cytoplasmic antiproteinase 2; CAP-2; CAP2; Peptidase inhibitor 8; PI-8 |
UniProt Gene Name: | SERPINB8 |
UniProt Entry Name: | SPB8_HUMAN |