SERPINB3 Antibody (PACO16681)
- SKU:
- PACO16681
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SERPINB3 Antibody (PACO16681) |
抗体コード: | PACO16681 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
反応性: | Human |
免疫原: | Fusion protein of human SERPINB3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela cells, 293T cells, LO2 cells, Primary antibody: PACO16681(SERPINB3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. |
バックグラウンド: | SERPINB3(serpin peptidase inhibitor, clade B (ovalbumin), member 3), also known as SCCA1, increase in advancing stages of some cervical, lung, esophageal and head and neck cancers). Human chromosome position 18q21.3 contains a cluster of serpins, including a tandem duplication of the SCCA gene, plasminogen activator inhibitor type 2, and maspin. SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid, protein that was originally isolated from a metastatic cervical squamous cell carcinoma. |
シノニム: | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
UniProt Protein Function: | SERPINB3: May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 18q21.3 Cellular Component: cytoplasm; cytoplasmic vesicle; extracellular space; nucleus; vesicle Molecular Function:cysteine protease inhibitor activity; protease binding; serine-type endopeptidase inhibitor activity; viral receptor activity Biological Process: negative regulation of catalytic activity; negative regulation of JNK activity; negative regulation of peptidase activity; negative regulation of proteolysis; positive regulation of cell migration; positive regulation of cell proliferation |
UniProt Code: | P29508 |
NCBI GenInfo Identifier: | 20141712 |
NCBI Gene ID: | 6317 |
NCBI Accession: | P29508.2 |
UniProt Secondary Accession: | P29508,Q53H28, Q53YB5, Q86VF3, Q86W04, Q8IWL4, Q8IXI3 Q96J21, Q9BYF8, A6NDM2, B2RBT5, B3W5Y6, |
UniProt Related Accession: | P29508 |
Molecular Weight: | 38,550 Da |
NCBI Full Name: | Serpin B3 |
NCBI Synonym Full Names: | serpin family B member 3 |
NCBI Official Symbol: | SERPINB3 |
NCBI Official Synonym Symbols: | SCC; T4-A; SCCA1; SSCA1; SCCA-1; HsT1196; SCCA-PD |
NCBI Protein Information: | serpin B3 |
UniProt Protein Name: | Serpin B3 |
UniProt Synonym Protein Names: | Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1 |
Protein Family: | Serpin |
UniProt Gene Name: | SERPINB3 |
UniProt Entry Name: | SPB3_HUMAN |
Antibodies | ELISA Kits |
Anti-SERPINB3 Antibody (CAB5418) | Human SerpinB3 ELISA Kit |
SERPINB3 Antibody (PACO02008) | Human Serpin B3 (SERPINB3) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |