SENP2 Antibody (PACO53934)
- SKU:
- PACO53934
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SENP2 Antibody (PACO53934) |
抗体コード: | PACO53934 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Sentrin-specific protease 2 protein (138-324AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Mouse liver tissue. All lanes: SENP2 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 68, 67 kDa. Observed band size: 68 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human breast cancer using PACO53934 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO53934 at dilution of 1:100. |
バックグラウンド: | Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB. |
シノニム: | Sentrin-specific protease 2 (EC 3.4.22) (Axam2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Sentrin/SUMO-specific protease SENP2), SENP2, KIAA1331 |
UniProt Protein Function: | SENP2: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Belongs to the peptidase C48 family. |
UniProt Protein Details: | Protein type:Protease; EC 3.4.22.68 Chromosomal Location of Human Ortholog: 3q27.2 Cellular Component: nuclear pore; nucleoplasm; PML body Molecular Function:endopeptidase activity; protein binding; SUMO-specific protease activity Biological Process: fat cell differentiation; negative regulation of protein ubiquitination; positive regulation of protein ubiquitination; protein destabilization; protein desumoylation; protein sumoylation |
NCBI Summary: | SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004] |
UniProt Code: | Q9HC62 |
NCBI GenInfo Identifier: | 143811458 |
NCBI Gene ID: | 59343 |
NCBI Accession: | Q9HC62.3 |
UniProt Secondary Accession: | Q9HC62,Q8IW97, Q96SR2, Q9P2L5, B4DQ42, |
UniProt Related Accession: | Q9HC62 |
Molecular Weight: | 66,358 Da |
NCBI Full Name: | Sentrin-specific protease 2 |
NCBI Synonym Full Names: | SUMO1/sentrin/SMT3 specific peptidase 2 |
NCBI Official Symbol: | SENP2 |
NCBI Official Synonym Symbols: | AXAM2; SMT3IP2 |
NCBI Protein Information: | sentrin-specific protease 2 |
UniProt Protein Name: | Sentrin-specific protease 2 |
UniProt Synonym Protein Names: | Axam2; SMT3-specific isopeptidase 2; Smt3ip2; Sentrin/SUMO-specific protease SENP2 |
Protein Family: | Sentrin-specific protease |
UniProt Gene Name: | SENP2 |
UniProt Entry Name: | SENP2_HUMAN |
Antibodies | ELISA Kits |
Anti-SENP2 Antibody (CAB17994) | SENP2 Colorimetric Cell-Based ELISA Kit |
SENP2 Antibody (PACO03060) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |