SENP1 Antibody (PACO20428)
- SKU:
- PACO20428
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SENP1 Antibody (PACO20428) |
抗体コード: | PACO20428 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Synthetic peptide of human SENP1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20428(SENP1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 6%SDS-PAGE, Lysate: 40 µg, Lane 1-2: Jurkat cells, Raji cells, Primary antibody: PACO20428(SENP1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20428(SENP1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants. |
シノニム: | SUMO1/sentrin specific peptidase 1 |
UniProt Protein Function: | SENP1: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity. Belongs to the peptidase C48 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.4.22.68; Protease; Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 12q13.1 Cellular Component: focal adhesion; nuclear membrane; nucleoplasm; nucleus Molecular Function:endopeptidase activity; protein binding; SUMO-specific protease activity Biological Process: caspase activation; positive regulation of transcription from RNA polymerase II promoter; protein desumoylation; protein sumoylation; proteolysis |
NCBI Summary: | This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
UniProt Code: | Q9P0U3 |
NCBI GenInfo Identifier: | 215273882 |
NCBI Gene ID: | 29843 |
NCBI Accession: | Q9P0U3.2 |
UniProt Secondary Accession: | Q9P0U3,Q86XC8, A8K7P5, |
UniProt Related Accession: | Q9P0U3 |
Molecular Weight: | 73,351 Da |
NCBI Full Name: | Sentrin-specific protease 1 |
NCBI Synonym Full Names: | SUMO1/sentrin specific peptidase 1 |
NCBI Official Symbol: | SENP1 |
NCBI Official Synonym Symbols: | SuPr-2 |
NCBI Protein Information: | sentrin-specific protease 1 |
UniProt Protein Name: | Sentrin-specific protease 1 |
UniProt Synonym Protein Names: | Sentrin/SUMO-specific protease SENP1 |
Protein Family: | Sentrin-specific protease |
UniProt Gene Name: | SENP1 |
UniProt Entry Name: | SENP1_HUMAN |
Antibodies | ELISA Kits |
Anti-SENP1 Antibody (CAB13086) | SENP1 Colorimetric Cell-Based ELISA Kit |
Anti-SENP1 Antibody (CAB4460) | |
SENP1 Antibody (PACO01480) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |