SEC23IP Antibody (PACO51242)
- SKU:
- PACO51242
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SEC23IP Antibody (PACO51242) |
抗体コード: | PACO51242 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human SEC23-interacting protein (779-989AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Hela whole cell lysate. All lanes: SEC23IP antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 112, 103 kDa. Observed band size: 112 kDa.. | |
Immunohistochemistry of paraffin-embedded human breast cancer using PACO51242 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO51242 at dilution of 1:100. |
バックグラウンド: | Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P). |
シノニム: | SEC23-interacting protein (p125), SEC23IP |
UniProt Protein Function: | SEC23IP: Plays a role in the organization of endoplasmic reticulum exit sites. Belongs to the PA-PLA1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Endoplasmic reticulum Chromosomal Location of Human Ortholog: 10q25-q26 Cellular Component: cis-Golgi network; intracellular membrane-bound organelle; cytoplasm; ER-Golgi intermediate compartment Molecular Function:metal ion binding Biological Process: acrosome formation; intracellular protein transport; single fertilization; Golgi organization and biogenesis |
NCBI Summary: | This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011] |
UniProt Code: | Q9Y6Y8 |
NCBI GenInfo Identifier: | 55584014 |
NCBI Gene ID: | 11196 |
NCBI Accession: | Q9Y6Y8.1 |
UniProt Related Accession: | Q9Y6Y8 |
Molecular Weight: | 102kDa; 111kDa |
NCBI Full Name: | SEC23-interacting protein |
NCBI Synonym Full Names: | SEC23 interacting protein |
NCBI Official Symbol: | SEC23IP |
NCBI Official Synonym Symbols: | P125; P125A; MSTP053 |
NCBI Protein Information: | SEC23-interacting protein |
UniProt Protein Name: | SEC23-interacting protein |
UniProt Synonym Protein Names: | p125 |
Protein Family: | SEC23-interacting protein |
UniProt Gene Name: | SEC23IP |
UniProt Entry Name: | S23IP_HUMAN |