Scn4b Antibody (PACO21276)
- SKU:
- PACO21276
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | Scn4b Antibody (PACO21276) |
抗体コード: | PACO21276 |
サイズ: | 100ul(100ug) |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Recombinant protein of mouse SCN4B |
憲法: | Liquid |
ストレージバッファ: | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts of U-87 cell lines, using SCN4B antibody. |
シノニム: | SCN4B; Gm1471 |
UniProt Protein Function: | SCN4B: Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Defects in SCN4B are the cause of long QT syndrome type 10 (LQT10). Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress. They can present with a sentinel event of sudden cardiac death in infancy. Belongs to the sodium channel auxiliary subunit SCN4B (TC 8.A.17) family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralCellular Component: voltage-gated sodium channel complex; membrane; integral to membrane; plasma membrane; intrinsic to plasma membraneMolecular Function: sodium channel regulator activity; voltage-gated sodium channel activity; voltage-gated ion channel activity; sodium channel activityBiological Process: transport; sodium ion transport; ion transport; cardiac muscle contraction |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q7M729 |
NCBI GenInfo Identifier: | 57012678 |
NCBI Gene ID: | 399548 |
NCBI Accession: | Q7M729.1 |
UniProt Secondary Accession: | Q7M729 |
UniProt Related Accession: | Q7M729 |
Molecular Weight: | 228 |
NCBI Full Name: | Sodium channel subunit beta-4 |
NCBI Synonym Full Names: | sodium channel, type IV, beta |
NCBI Official Symbol: | Scn4b |
NCBI Official Synonym Symbols: | Gm1471 |
NCBI Protein Information: | sodium channel subunit beta-4; sodium channel beta 4 subunit; sodium channel accessory subunit; sodium channel, type IV, beta polypeptide; voltage gated sodium channel beta 4 subunit |
UniProt Protein Name: | Sodium channel subunit beta-4 |
UniProt Synonym Protein Names: | |
Protein Family: | Sodium channel |
UniProt Gene Name: | Scn4b |
UniProt Entry Name: | SCN4B_MOUSE |