S1PR3 Antibody, FITC conjugated (PACO40280)
- SKU:
- PACO40280
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | S1PR3 Antibody, FITC conjugated (PACO40280) |
抗体コード: | PACO40280 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Sphingosine 1-phosphate receptor 3 protein (303-378AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. |
シノニム: | Sphingosine 1-phosphate receptor 3 (S1P receptor 3) (S1P3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor Edg-3) (S1P receptor Edg-3), S1PR3, EDG3 |
UniProt Protein Function: | S1PR3: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 9q22.1-q22.2 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; integrin binding; lipid binding; protein binding Biological Process: anatomical structure morphogenesis; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; positive regulation of cell proliferation |
NCBI Summary: | This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q99500 |
NCBI GenInfo Identifier: | 42560554 |
NCBI Gene ID: | 1903 |
NCBI Accession: | Q99500.2 |
UniProt Secondary Accession: | Q99500,Q5SQD8, Q7Z5I2, |
UniProt Related Accession: | Q99500 |
Molecular Weight: | 42,250 Da |
NCBI Full Name: | Sphingosine 1-phosphate receptor 3 |
NCBI Synonym Full Names: | sphingosine-1-phosphate receptor 3 |
NCBI Official Symbol: | S1PR3 |
NCBI Official Synonym Symbols: | EDG3; LPB3; S1P3; EDG-3 |
NCBI Protein Information: | sphingosine 1-phosphate receptor 3 |
UniProt Protein Name: | Sphingosine 1-phosphate receptor 3 |
UniProt Synonym Protein Names: | Endothelial differentiation G-protein coupled receptor 3; Sphingosine 1-phosphate receptor Edg-3; S1P receptor Edg-3 |
Protein Family: | Sphingosine 1-phosphate receptor |
UniProt Gene Name: | S1PR3 |
UniProt Entry Name: | S1PR3_HUMAN |