RXFP2 Antibody (PACO56478)
- SKU:
- PACO56478
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RXFP2 Antibody (PACO56478) |
抗体コード: | PACO56478 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Relaxin receptor 2 protein (33-158AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: A549 whole cell lysate. All lanes: RXFP2 antibody at 4.6µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 87, 84 kDa. Observed band size: 87 kDa. |
![]() | IHC image of PACO56478 diluted at 1:290 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | IHC image of PACO56478 diluted at 1:290 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). |
シノニム: | Relaxin receptor 2 (G-protein coupled receptor 106) (G-protein coupled receptor affecting testicular descent) (Leucine-rich repeat-containing G-protein coupled receptor 8) (Relaxin family peptide receptor 2), RXFP2, GPR106 GREAT LGR8 |
UniProt Protein Function: | LGR8: the relaxin receptor is a G-protein coupled receptor (GPCR) that leads to the stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). |
UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1 Chromosomal Location of Human Ortholog: 13q13.1 Cellular Component: plasma membrane Molecular Function:G-protein coupled receptor activity Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger Disease: Cryptorchidism, Unilateral Or Bilateral |
NCBI Summary: | This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] |
UniProt Code: | Q8WXD0 |
NCBI GenInfo Identifier: | 21362625 |
NCBI Gene ID: | 122042 |
NCBI Accession: | Q8WXD0.1 |
UniProt Secondary Accession: | Q8WXD0,Q3KU23, B1ALE9, |
UniProt Related Accession: | Q8WXD0 |
Molecular Weight: | 83,736 Da |
NCBI Full Name: | Relaxin receptor 2 |
NCBI Synonym Full Names: | relaxin/insulin like family peptide receptor 2 |
NCBI Official Symbol: | RXFP2 |
NCBI Official Synonym Symbols: | LGR8; GREAT; GPR106; INSL3R; LGR8.1; RXFPR2 |
NCBI Protein Information: | relaxin receptor 2 |
UniProt Protein Name: | Relaxin receptor 2 |
UniProt Synonym Protein Names: | G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2 |
Protein Family: | Relaxin receptor |
UniProt Gene Name: | RXFP2 |
UniProt Entry Name: | RXFP2_HUMAN |