RUSC1 Antibody, Biotin conjugated (PACO40981)
- SKU:
- PACO40981
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | RUSC1 Antibody, Biotin conjugated (PACO40981) |
抗体コード: | PACO40981 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human RUN and SH3 domain-containing protein 1 protein (231-433AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway. |
シノニム: | RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca), RUSC1, NESCA |
UniProt Protein Function: | RUSC1: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF- dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 1q21-q22 Cellular Component: microtubule cytoskeleton; Golgi apparatus; postsynaptic membrane; microtubule; postsynaptic density; cytoplasmic membrane-bound vesicle; early endosome; cytoplasm; cytoplasmic vesicle; cell junction; nucleus Molecular Function:protein binding; SH3/SH2 adaptor activity; actin binding Biological Process: protein polyubiquitination; positive regulation of signal transduction |
UniProt Code: | Q9BVN2 |
NCBI GenInfo Identifier: | 157412245 |
NCBI Gene ID: | 23623 |
NCBI Accession: | NP_001098673 |
UniProt Related Accession: | Q9BVN2 |
Molecular Weight: | 55; 100kDa |
NCBI Full Name: | RUN and SH3 domain-containing protein 1 isoform a |
NCBI Synonym Full Names: | RUN and SH3 domain containing 1 |
NCBI Official Symbol: | RUSC1 |
NCBI Official Synonym Symbols: | NESCA |
NCBI Protein Information: | RUN and SH3 domain-containing protein 1 |
UniProt Protein Name: | RUN and SH3 domain-containing protein 1 |
UniProt Synonym Protein Names: | New molecule containing SH3 at the carboxy-terminus; Nesca |
Protein Family: | RUN and SH3 domain-containing protein |
UniProt Gene Name: | RUSC1 |
UniProt Entry Name: | RUSC1_HUMAN |