RPS7 Antibody, HRP conjugated (PACO55763)
- SKU:
- PACO55763
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Description
抗体名: | RPS7 Antibody, HRP conjugated (PACO55763) |
抗体コード: | PACO55763 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human 40S ribosomal protein S7 protein (1-194AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Required for rRNA maturation. |
シノニム: | 40S ribosomal protein S7 (Small ribosomal subunit protein eS7), RPS7 |
UniProt Protein Function: | RPS7: Required for rRNA maturation. Defects in RPS7 are the cause of Diamond-Blackfan anemia type 8 (DBA8). DBA8 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Belongs to the ribosomal protein S7e family. |
UniProt Protein Details: | Protein type:Ribosomal; Translation Chromosomal Location of Human Ortholog: 2p25 Cellular Component: small subunit processome; focal adhesion; membrane; cytoplasm; nucleolus; ribosome; microtubule organizing center; cytosol; ribonucleoprotein complex; nucleus Molecular Function:protein binding; structural constituent of ribosome; RNA binding Biological Process: SRP-dependent cotranslational protein targeting to membrane; translation; viral reproduction; translational termination; viral infectious cycle; ribosomal small subunit biogenesis and assembly; translational elongation; cellular protein metabolic process; translational initiation; mRNA catabolic process, nonsense-mediated decay; viral transcription; gene expression; rRNA processing Disease: Diamond-blackfan Anemia 8 |
NCBI Summary: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
UniProt Code: | P62081 |
NCBI GenInfo Identifier: | 49065831 |
NCBI Gene ID: | 6201 |
NCBI Accession: | P62081.1 |
UniProt Secondary Accession: | P62081,P23821, P24818, Q57Z92, Q6IPH1, |
UniProt Related Accession: | P62081 |
Molecular Weight: | 194 |
NCBI Full Name: | 40S ribosomal protein S7 |
NCBI Synonym Full Names: | ribosomal protein S7 |
NCBI Official Symbol: | RPS7 |
NCBI Official Synonym Symbols: | S7; DBA8 |
NCBI Protein Information: | 40S ribosomal protein S7 |
UniProt Protein Name: | 40S ribosomal protein S7 |
Protein Family: | Ribosomal protein |
UniProt Gene Name: | RPS7 |
UniProt Entry Name: | RS7_HUMAN |