バックグラウンド: | cytosol, cytosolic small ribosomal subunit, membrane, nucleoplasm, nucleus, polysome, RNA binding, structural constituent of ribosome, multicellular organism development, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
シノニム: | 40S ribosomal protein S4, Y isoform 1 (Small ribosomal subunit protein eS4), RPS4Y1, RPS4Y |
UniProt Protein Function: | RPS4Y1: Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]Protein type: Ribosomal; TranslationChromosomal Location of Human Ortholog: Yp11.3Cellular Component: cytosol; membrane; nucleoplasm; nucleus; polysomeMolecular Function: RNA binding; structural constituent of ribosomeBiological Process: mRNA catabolic process, nonsense-mediated decay; multicellular organismal development; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription |
UniProt Protein Details: | |
NCBI Summary: | Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
UniProt Code: | P22090 |
NCBI GenInfo Identifier: | 133948 |
NCBI Gene ID: | 6192 |
NCBI Accession: | P22090.2 |
UniProt Secondary Accession: | P22090,A8K9V4 |
UniProt Related Accession: | P22090 |
Molecular Weight: | 29,456 Da |
NCBI Full Name: | 40S ribosomal protein S4, Y isoform 1 |
NCBI Synonym Full Names: | ribosomal protein S4, Y-linked 1 |
NCBI Official Symbol: | RPS4Y1 |
NCBI Official Synonym Symbols: | S4; RPS4Y |
NCBI Protein Information: | 40S ribosomal protein S4, Y isoform 1 |
UniProt Protein Name: | 40S ribosomal protein S4, Y isoform 1 |
UniProt Synonym Protein Names: | |
Protein Family: | 40S ribosomal protein |
UniProt Gene Name: | RPS4Y1 |
UniProt Entry Name: | RS4Y1_HUMAN |