RPH3A Antibody (PACO01390)
- SKU:
- PACO01390
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RPH3A Antibody |
抗体コード: | PACO01390 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from human Rabphilin-3A around the non-phosphorylation site of S237. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | RPH3A; KIAA0985; Rabphilin-3A; Exophilin-1 |
UniProt Protein Function: | rabphilin 3A: Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 12q24.13 Cellular Component: Golgi apparatus; synaptic vesicle; neuron projection; protein complex; extrinsic to membrane; synaptic vesicle membrane; synapse; cell junction; cytosol; secretory granule Molecular Function:phosphatidylinositol-4,5-bisphosphate binding; selenium binding; protein binding; zinc ion binding; calcium-dependent phospholipid binding; transporter activity; protein complex binding; calcium ion binding; phosphate binding; Rab GTPase binding Biological Process: intracellular protein transport |
NCBI Summary: | Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al., 2007 [PubMed 17149709]).[supplied by OMIM, Jul 2008] |
UniProt Code: | Q9Y2J0 |
NCBI GenInfo Identifier: | 13878745 |
NCBI Gene ID: | 22895 |
NCBI Accession: | Q9Y2J0.1 |
UniProt Secondary Accession: | Q9Y2J0,Q96AE0, B7Z3C3, |
UniProt Related Accession: | Q9Y2J0 |
Molecular Weight: | 694 |
NCBI Full Name: | Rabphilin-3A |
NCBI Synonym Full Names: | rabphilin 3A |
NCBI Official Symbol: | RPH3A |
NCBI Protein Information: | rabphilin-3A; exophilin-1; rabphilin 3A homolog |
UniProt Protein Name: | Rabphilin-3A |
UniProt Synonym Protein Names: | Exophilin-1 |
Protein Family: | Rabphilin |
UniProt Gene Name: | RPH3A |
UniProt Entry Name: | RP3A_HUMAN |