RPA3 Antibody (PACO33672)
- SKU:
- PACO33672
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | RPA3 Antibody (PACO33672) |
抗体コード: | PACO33672 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
反応性: | Human |
免疫原: | Recombinant Human Replication protein A 14 kDa subunit protein (1-119AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: RPA3 antibody at 2µg/ml Lane 1: LO2 whole cell lysate Lane 2: HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 14 kDa Observed band size: 14 kDa . |
バックグラウンド: | Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Ref.7 Ref.9 Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase α but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. |
シノニム: | Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3), RPA3, REPA3 RPA14 |
UniProt Protein Function: | RPA3: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 7p22 Cellular Component: nucleoplasm; DNA replication factor A complex Molecular Function:protein binding; damaged DNA binding; single-stranded DNA binding Biological Process: mismatch repair; regulation of mitotic cell cycle; DNA strand elongation during DNA replication; DNA repair; double-strand break repair via homologous recombination; regulation of cell proliferation; telomere maintenance via semi-conservative replication; DNA recombinase assembly; nucleotide-excision repair; base-excision repair; double-strand break repair; transcription-coupled nucleotide-excision repair; telomere maintenance via recombination; nucleotide-excision repair, DNA damage removal; nucleotide-excision repair, DNA gap filling; mitotic cell cycle; DNA replication; telomere maintenance; G1/S transition of mitotic cell cycle |
UniProt Code: | P35244 |
NCBI GenInfo Identifier: | 464608 |
NCBI Gene ID: | 6119 |
NCBI Accession: | P35244.1 |
UniProt Secondary Accession: | P35244,Q549U6, |
UniProt Related Accession: | P35244 |
Molecular Weight: | 121 |
NCBI Full Name: | Replication protein A 14 kDa subunit |
NCBI Synonym Full Names: | replication protein A3, 14kDa |
NCBI Official Symbol: | RPA3 |
NCBI Official Synonym Symbols: | REPA3 |
NCBI Protein Information: | replication protein A 14 kDa subunit; RP-A p14; RF-A protein 3; replication factor A protein 3 |
UniProt Protein Name: | Replication protein A 14 kDa subunit |
UniProt Synonym Protein Names: | Replication factor A protein 3; RF-A protein 3 |
Protein Family: | Replication protein |
UniProt Gene Name: | RPA3 |
UniProt Entry Name: | RFA3_HUMAN |