RNH1 Antibody (PACO16986)
- SKU:
- PACO16986
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RNH1 Antibody (PACO16986) |
抗体コード: | PACO16986 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Fusion protein of human RNH1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO16986(RNH1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-5: HT29 cells, human normal kidney tissue, Lo2 cells, human normal liver tissue, human fetal brain tissue, Primary antibody: PACO16986(RNH1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16986(RNH1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. |
シノニム: | ribonuclease/angiogenin inhibitor 1 |
UniProt Protein Function: | RNH1: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis. |
UniProt Protein Details: | Protein type:Inhibitor Chromosomal Location of Human Ortholog: 11p15.5 Cellular Component: angiogenin-PRI complex; cytoplasm Molecular Function:protein binding; ribonuclease inhibitor activity Biological Process: negative regulation of catalytic activity; mRNA catabolic process; regulation of angiogenesis |
NCBI Summary: | Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010] |
UniProt Code: | P13489 |
NCBI GenInfo Identifier: | 132573 |
NCBI Gene ID: | 6050 |
NCBI Accession: | P13489.2 |
UniProt Secondary Accession: | P13489,Q8IZK8, Q96FD7, Q9BQ80, Q9UDK6, |
UniProt Related Accession: | P13489 |
Molecular Weight: | |
NCBI Full Name: | Ribonuclease inhibitor |
NCBI Synonym Full Names: | ribonuclease/angiogenin inhibitor 1 |
NCBI Official Symbol: | RNH1 |
NCBI Official Synonym Symbols: | RAI; RNH |
NCBI Protein Information: | ribonuclease inhibitor; placental RNase inhibitor; placental ribonuclease inhibitor |
UniProt Protein Name: | Ribonuclease inhibitor |
UniProt Synonym Protein Names: | Placental ribonuclease inhibitor; Placental RNase inhibitor; Ribonuclease/angiogenin inhibitor 1; RAI |
Protein Family: | Ribonuclease inhibitor |
UniProt Gene Name: | RNH1 |
UniProt Entry Name: | RINI_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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