RNF220 Antibody (PACO60088)
- SKU:
- PACO60088
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RNF220 Antibody (PACO60088) |
抗体コード: | PACO60088 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:500-1:1000 |
反応性: | Human |
免疫原: | Recombinant Human E3 ubiquitin-protein ligase RNF220 protein (384-472AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO60088 diluted at 1:500 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling. |
シノニム: | E3 ubiquitin-protein ligase RNF220 (EC 2.3.2.27) (RING finger protein 220) (RING-type E3 ubiquitin transferase RNF220), RNF220, C1orf164 |
UniProt Code: | Q5VTB9 |
NCBI GenInfo Identifier: | 46397375 |
NCBI Gene ID: | 55182 |
NCBI Accession: | NP_060620.2 |
UniProt Related Accession: | Q5VTB9 |
Molecular Weight: | Calculated: 39kDa; 62kDaObserved: 75kDa |
NCBI Full Name: | E3 ubiquitin-protein ligase RNF220 isoform 1 |
NCBI Synonym Full Names: | ring finger protein 220 |
NCBI Official Symbol: | RNF220 |
NCBI Official Synonym Symbols: | C1orf164 |
NCBI Protein Information: | E3 ubiquitin-protein ligase RNF220 |
UniProt Protein Name: | E3 ubiquitin-protein ligase RNF220 |
UniProt Synonym Protein Names: | RING finger protein 220 |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | RNF220 |
UniProt Entry Name: | RN220_HUMAN |
Antibodies |
Anti-RNF220 Antibody (CAB15853) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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