RNF114 Antibody (PACO45196)
- SKU:
- PACO45196
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RNF114 Antibody (PACO45196) |
抗体コード: | PACO45196 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human E3 ubiquitin-protein ligase RNF114 protein (1-228AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: RNF114 antibody at 1.63µg/ml. Lane 1: 293T whole cell lysate. Lane 2: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 26, 22 kDa. Observed band size: 26 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO45196 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human skin tissue using PACO45196 at dilution of 1:100. |
バックグラウンド: | E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis. |
シノニム: | E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313), RNF114, ZNF228 ZNF313 |
UniProt Protein Function: | ZNF313: May play a role in spermatogenesis. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Ubiquitin conjugating system; Ubiquitin ligase; Transcription factorChromosomal Location of Human Ortholog: 20q13.13Cellular Component: cytosol; intracellularMolecular Function: ubiquitin conjugating enzyme binding; ubiquitin-protein ligase activityBiological Process: positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9Y508 |
NCBI GenInfo Identifier: | 8923898 |
NCBI Gene ID: | 55905 |
NCBI Accession: | NP_061153.1 |
UniProt Secondary Accession: | Q9Y508,Q6N0B0, B2RDQ9, B4DWY5, E1P627 |
UniProt Related Accession: | Q9Y508 |
Molecular Weight: | 21,004 Da |
NCBI Full Name: | E3 ubiquitin-protein ligase RNF114 |
NCBI Synonym Full Names: | ring finger protein 114 |
NCBI Official Symbol: | RNF114 |
NCBI Official Synonym Symbols: | ZNF313; PSORS12 |
NCBI Protein Information: | E3 ubiquitin-protein ligase RNF114 |
UniProt Protein Name: | E3 ubiquitin-protein ligase RNF114 |
UniProt Synonym Protein Names: | RING finger protein 114; Zinc finger protein 228; Zinc finger protein 313 |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | RNF114 |
UniProt Entry Name: | RN114_HUMAN |