RNASEH1 Antibody, FITC conjugated (PACO58875)
- SKU:
- PACO58875
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | RNASEH1 Antibody, FITC conjugated (PACO58875) |
抗体コード: | PACO58875 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Ribonuclease H1 protein (73-185AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II. |
シノニム: | Ribonuclease H1 (RNase H1) (EC 3.1.26.4) (Ribonuclease H type II), RNASEH1, RNH1 |
NCBI Summary: | This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17. [provided by RefSeq, Jul 2017] |
UniProt Code: | O60930 |
NCBI GenInfo Identifier: | 21359816 |
NCBI Gene ID: | 246243 |
NCBI Accession: | NP_002927 |
UniProt Related Accession: | O60930 |
Molecular Weight: | Predicted Molecular Mass: 62.1kDaAccurate Molecular Mass: 62kDa |
NCBI Full Name: | ribonuclease H1 isoform 1 |
NCBI Synonym Full Names: | ribonuclease H1 |
NCBI Official Symbol: | RNASEH1 |
NCBI Official Synonym Symbols: | RNH1; H1RNA; PEOB2 |
NCBI Protein Information: | ribonuclease H1 |
UniProt Protein Name: | Ribonuclease H1 |
UniProt Synonym Protein Names: | Ribonuclease H type II |
Protein Family: | Ribonuclease |
UniProt Gene Name: | RNASEH1 |
UniProt Entry Name: | RNH1_HUMAN |