RHOD Antibody, HRP conjugated (PACO56957)
- SKU:
- PACO56957
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | RHOD Antibody, HRP conjugated (PACO56957) |
抗体コード: | PACO56957 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Rho-related GTP-binding protein RhoD protein (1-80AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution. |
シノニム: | Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1), RHOD, ARHD |
UniProt Protein Function: | RHOD: Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton. Belongs to the small GTPase superfamily. Rho family. |
UniProt Protein Details: | Protein type:G protein; G protein, monomeric, Rho; G protein, monomeric; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 11q14.3 Cellular Component: early endosome; plasma membrane; cytosol Molecular Function:GTPase activity; GTP binding; protein kinase binding Biological Process: focal adhesion formation; lamellipodium biogenesis; actin filament bundle formation; regulation of small GTPase mediated signal transduction; positive regulation of cell adhesion; metabolic process; small GTPase mediated signal transduction; regulation of focal adhesion formation; Rho protein signal transduction; protein targeting; positive regulation of cell migration |
NCBI Summary: | Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
UniProt Code: | O00212 |
NCBI GenInfo Identifier: | 254763327 |
NCBI Gene ID: | 29984 |
NCBI Accession: | O00212.2 |
UniProt Related Accession: | O00212 |
Molecular Weight: | 210 |
NCBI Full Name: | Rho-related GTP-binding protein RhoD |
NCBI Synonym Full Names: | ras homolog family member D |
NCBI Official Symbol: | RHOD |
NCBI Official Synonym Symbols: | Rho; ARHD; RHOM; RHOHP1 |
NCBI Protein Information: | rho-related GTP-binding protein RhoD; ras homolog D; Rho-related protein HP1; ras homolog gene family, member A; ras homolog gene family, member D |
UniProt Protein Name: | Rho-related GTP-binding protein RhoD |
UniProt Synonym Protein Names: | Rho-related protein HP1; RhoHP1 |
Protein Family: | Rhodopsin |
UniProt Gene Name: | RHOD |
UniProt Entry Name: | RHOD_HUMAN |