Rgn Antibody (PACO29480)
- SKU:
- PACO29480
- Product type:
- Antibody
- Reactivity:
- Rat
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | Rgn Antibody (PACO29480) |
抗体コード: | PACO29480 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
反応性: | Rat, Human |
免疫原: | Recombinant Rat Regucalcin protein (1-299AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: Rgn antibody at 8µg/ml Lane 1: A549 whole cell lysate Lane 2: HCT116 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 34 kDa Observed band size: 34 kDa . |
バックグラウンド: | Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid, (vitamin C) biosynthesis. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities. |
シノニム: | Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30), Rgn, Smp30 |
UniProt Protein Function: | RGN: Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities. Belongs to the SMP-30/CGR1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.1.1.17 Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus Molecular Function:calcium ion binding; enzyme regulator activity; gluconolactonase activity; zinc ion binding Biological Process: aging; cellular calcium ion homeostasis; kidney development; L-ascorbic acid biosynthetic process; liver development; negative regulation of apoptosis; negative regulation of cyclic-nucleotide phosphodiesterase activity; negative regulation of epithelial cell proliferation; negative regulation of nitric oxide biosynthetic process; negative regulation of phosphoprotein phosphatase activity; negative regulation of protein amino acid phosphorylation; negative regulation of protein kinase activity; positive regulation of ATPase activity; positive regulation of fatty acid biosynthetic process; positive regulation of GTPase activity; regulation of calcium-mediated signaling; spermatogenesis |
NCBI Summary: | binds calcium ions; induces increased activity of the sarcoplasmic reticulum calcium-transporting ATPase [RGD, Feb 2006] |
UniProt Code: | Q03336 |
NCBI GenInfo Identifier: | 13928740 |
NCBI Gene ID: | 25106 |
NCBI Accession: | NP_113734.1 |
UniProt Secondary Accession: | Q03336,Q63496, Q925W3, Q9QWP2, |
UniProt Related Accession: | Q03336 |
Molecular Weight: | 35.4 kDa |
NCBI Full Name: | regucalcin |
NCBI Synonym Full Names: | regucalcin (senescence marker protein-30) |
NCBI Official Symbol: | Rgn |
NCBI Official Synonym Symbols: | Rc; GNL; Reguc |
NCBI Protein Information: | regucalcin |
UniProt Protein Name: | Regucalcin |
UniProt Synonym Protein Names: | Gluconolactonase (EC:3.1.1.17); GNL; Senescence marker protein 30; SMP-30 |
Protein Family: | Regucalcin |
UniProt Gene Name: | Rgn |
UniProt Entry Name: | RGN_RAT |
ELISA Kits |
Rat Regucalcin (Rgn) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |