RGN Antibody, Biotin conjugated (PACO54493)
- SKU:
- PACO54493
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | RGN Antibody, Biotin conjugated (PACO54493) |
抗体コード: | PACO54493 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Regucalcin protein (1-299AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity). |
シノニム: | Regucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30), RGN, SMP30 |
UniProt Protein Function: | RGN: Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities. Belongs to the SMP-30/CGR1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.1.1.17 Chromosomal Location of Human Ortholog: Xp11.3 Cellular Component: nucleoplasm; cytoplasm; nucleus Molecular Function:zinc ion binding; gluconolactonase activity; calcium ion binding; enzyme regulator activity Biological Process: cellular calcium ion homeostasis; L-ascorbic acid biosynthetic process; positive regulation of ATPase activity; regulation of calcium-mediated signaling |
NCBI Summary: | The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
UniProt Code: | Q15493 |
NCBI GenInfo Identifier: | 3334328 |
NCBI Gene ID: | 9104 |
NCBI Accession: | Q15493.1 |
UniProt Related Accession: | Q15493 |
Molecular Weight: | 33 kDa |
NCBI Full Name: | Regucalcin |
NCBI Synonym Full Names: | regucalcin |
NCBI Official Symbol: | RGN |
NCBI Official Synonym Symbols: | RC; GNL; SMP30; HEL-S-41 |
NCBI Protein Information: | regucalcin |
UniProt Protein Name: | Regucalcin |
UniProt Synonym Protein Names: | Gluconolactonase (EC:3.1.1.17); GNL; Senescence marker protein 30; SMP-30 |
Protein Family: | Regucalcin |
UniProt Gene Name: | RGN |
UniProt Entry Name: | RGN_HUMAN |