RFX2 Antibody, HRP conjugated (PACO56949)
- SKU:
- PACO56949
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | RFX2 Antibody, HRP conjugated (PACO56949) |
抗体コード: | PACO56949 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human DNA-binding protein RFX2 protein (1-130AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function (By similarity). Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis-specific histone gene HIST1H1T (By similarity). |
シノニム: | DNA-binding protein RFX2 (Regulatory factor X 2), RFX2 |
UniProt Protein Function: | RFX2: a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytoplasm; nucleus Molecular Function:DNA binding; transcription factor activity Biological Process: acrosome formation; cilium biogenesis; regulation of transcription from RNA polymerase II promoter; spermatid development |
NCBI Summary: | This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008] |
UniProt Code: | P48378 |
NCBI GenInfo Identifier: | 254763325 |
NCBI Gene ID: | 5990 |
NCBI Accession: | P48378.2 |
UniProt Secondary Accession: | P48378,Q6IQ44, Q8SNA2, A8K581, B3KNC4, |
UniProt Related Accession: | P48378 |
Molecular Weight: | 77,268 Da |
NCBI Full Name: | DNA-binding protein RFX2 |
NCBI Synonym Full Names: | regulatory factor X2 |
NCBI Official Symbol: | RFX2 |
NCBI Protein Information: | DNA-binding protein RFX2 |
UniProt Protein Name: | DNA-binding protein RFX2 |
UniProt Synonym Protein Names: | Regulatory factor X 2 |
Protein Family: | RFX-like DNA-binding protein |
UniProt Gene Name: | RFX2 |
UniProt Entry Name: | RFX2_HUMAN |