RFK Antibody, HRP conjugated (PACO38395)
- SKU:
- PACO38395
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | RFK Antibody, HRP conjugated (PACO38395) |
抗体コード: | PACO38395 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Riboflavin kinase protein (1-154AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase. |
シノニム: | Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin 5'-phosphotransferase) (Flavokinase), RFK |
UniProt Protein Function: | RFK: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN). |
UniProt Protein Details: | Protein type:Kinase, other; EC 2.7.1.26; Cofactor and Vitamin Metabolism - riboflavin Chromosomal Location of Human Ortholog: 9q21.13 Cellular Component: cytosol Molecular Function:riboflavin kinase activity Biological Process: apoptosis; positive regulation of NAD(P)H oxidase activity; riboflavin metabolic process |
NCBI Summary: | Riboflavin kinase (RFK; EC 2.7.1.26) is an essential enzyme that catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN), an obligatory step in vitamin B2 utilization and flavin cofactor synthesis (Karthikeyan et al., 2003 [PubMed 12623014]).[supplied by OMIM, Nov 2009] |
UniProt Code: | Q969G6 |
NCBI GenInfo Identifier: | 209572667 |
NCBI Gene ID: | 55312 |
NCBI Accession: | Q969G6.2 |
UniProt Secondary Accession: | Q969G6,Q5JSG9, Q9NUT7, |
UniProt Related Accession: | Q969G6 |
Molecular Weight: | 17,623 Da |
NCBI Full Name: | Riboflavin kinase |
NCBI Synonym Full Names: | riboflavin kinase |
NCBI Official Symbol: | RFK |
NCBI Official Synonym Symbols: | RIFK |
NCBI Protein Information: | riboflavin kinase |
UniProt Protein Name: | Riboflavin kinase |
UniProt Synonym Protein Names: | ATP:riboflavin 5'-phosphotransferase; Flavokinase |
UniProt Gene Name: | RFK |
UniProt Entry Name: | RIFK_HUMAN |