RBMS1 Antibody (PACO18383)
- SKU:
- PACO18383
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 抗体名: | RBMS1 Antibody (PACO18383) |
| 抗体コード: | PACO18383 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Synthetic peptide of human RBMS1 |
| 憲法: | Liquid |
| ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 精製方法: | Antigen affinity purification |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18383(RBMS1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18383(RBMS1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| バックグラウンド: | his gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. |
| シノニム: | RNA binding motif, single stranded interacting protein 1 |
| UniProt Protein Function: | RBMS1: Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA replication; RNA-binding Chromosomal Location of Human Ortholog: 2q24.2 Cellular Component: nucleus Molecular Function:protein binding; RNA binding; double-stranded DNA binding; nucleotide binding; single-stranded DNA binding Biological Process: RNA processing; DNA replication |
| NCBI Summary: | This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009] |
| UniProt Code: | P29558 |
| NCBI GenInfo Identifier: | 55977783 |
| NCBI Gene ID: | 5937 |
| NCBI Accession: | P29558.3 |
| UniProt Related Accession: | P29558 |
| Molecular Weight: | |
| NCBI Full Name: | RNA-binding motif, single-stranded-interacting protein 1 |
| NCBI Synonym Full Names: | RNA binding motif single stranded interacting protein 1 |
| NCBI Official Symbol: | RBMS1 |
| NCBI Official Synonym Symbols: | YC1; MSSP; SCR2; HCC-4; MSSP-1; MSSP-2; MSSP-3; C2orf12 |
| NCBI Protein Information: | RNA-binding motif, single-stranded-interacting protein 1 |
| UniProt Protein Name: | RNA-binding motif, single-stranded-interacting protein 1 |
| UniProt Synonym Protein Names: | Single-stranded DNA-binding protein MSSP-1; Suppressor of CDC2 with RNA-binding motif 2 |
| Protein Family: | RNA-binding motif, single-stranded-interacting protein |
| UniProt Gene Name: | RBMS1 |
| UniProt Entry Name: | RBMS1_HUMAN |