RBM22 Antibody, Biotin conjugated (PACO42273)
- SKU:
- PACO42273
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | RBM22 Antibody, Biotin conjugated (PACO42273) |
抗体コード: | PACO42273 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Pre-mRNA-splicing factor RBM22 protein (2-250AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses. |
シノニム: | Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) (Zinc finger CCCH domain-containing protein 16), RBM22, ZC3H16 |
UniProt Protein Function: | RBM22: Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses. Belongs to the SLT11 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding; RNA splicing; RNA processing; Spliceosome Chromosomal Location of Human Ortholog: 5q33.1 Cellular Component: cytoplasm; nucleoplasm; nucleus Molecular Function:calcium-dependent protein binding; nucleocytoplasmic transporter activity; protein binding; U6 snRNA binding Biological Process: nuclear mRNA cis splicing, via U2-type spliceosome; nuclear mRNA splicing, via spliceosome; positive regulation of RNA splicing; protein import into nucleus, translocation; spliceosomal snRNP biogenesis |
NCBI Summary: | This gene encodes an RNA binding protein. The encoded protein may play a role in cell division and may be involved in pre-mRNA splicing. Related pseudogenes exist on chromosomes 6, 7, 9, 13, 16, 18, and X. [provided by RefSeq, Mar 2009] |
UniProt Code: | Q9NW64 |
NCBI GenInfo Identifier: | 74762758 |
NCBI Gene ID: | 55696 |
NCBI Accession: | Q9NW64.1 |
UniProt Secondary Accession: | Q9NW64,O95607, A6NDM5, B4DLI9, |
UniProt Related Accession: | Q9NW64 |
Molecular Weight: | 41,152 Da |
NCBI Full Name: | Pre-mRNA-splicing factor RBM22 |
NCBI Synonym Full Names: | RNA binding motif protein 22 |
NCBI Official Symbol: | RBM22 |
NCBI Official Synonym Symbols: | Cwc2; ZC3H16; fSAP47 |
NCBI Protein Information: | pre-mRNA-splicing factor RBM22 |
UniProt Protein Name: | Pre-mRNA-splicing factor RBM22 |
UniProt Synonym Protein Names: | RNA-binding motif protein 22; Zinc finger CCCH domain-containing protein 16 |
Protein Family: | Pre-mRNA-splicing factor |
UniProt Gene Name: | RBM22 |
UniProt Entry Name: | RBM22_HUMAN |