RBM17 Antibody (PACO45618)
- SKU:
- PACO45618
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RBM17 Antibody (PACO45618) |
抗体コード: | PACO45618 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Splicing factor 45 protein (1-240AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: RBM17 antibody at 2.35µg/ml + U251 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 45 kDa. Observed band size: 45 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO45618 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO45618 at dilution of 1:100. |
バックグラウンド: | Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. |
シノニム: | Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17), RBM17, SPF45 |
UniProt Protein Function: | RBM17: Splice factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. |
UniProt Protein Details: | Protein type:RNA splicing; RNA-binding; Spliceosome Chromosomal Location of Human Ortholog: 10p15.1 Cellular Component: nucleoplasm; spliceosome Molecular Function:protein binding; RNA binding; nucleotide binding Biological Process: alternative nuclear mRNA splicing, via spliceosome |
NCBI Summary: | This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009] |
UniProt Code: | Q96I25 |
NCBI GenInfo Identifier: | 34925383 |
NCBI Gene ID: | 84991 |
NCBI Accession: | Q96I25.1 |
UniProt Secondary Accession: | Q96I25,Q96GY6, |
UniProt Related Accession: | Q96I25 |
Molecular Weight: | 401 |
NCBI Full Name: | Splicing factor 45 |
NCBI Synonym Full Names: | RNA binding motif protein 17 |
NCBI Official Symbol: | RBM17 |
NCBI Official Synonym Symbols: | SPF45 |
NCBI Protein Information: | splicing factor 45; splicing factor 45kDa; 45 kDa-splicing factor; RNA-binding motif protein 17 |
UniProt Protein Name: | Splicing factor 45 |
UniProt Synonym Protein Names: | 45 kDa-splicing factor; RNA-binding motif protein 17 |
Protein Family: | Splicing factor |
UniProt Gene Name: | RBM17 |
UniProt Entry Name: | SPF45_HUMAN |