RASA4 Antibody (PACO16939)
- SKU:
- PACO16939
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RASA4 Antibody (PACO16939) |
抗体コード: | PACO16939 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:10-1:50 |
反応性: | Human, Mouse |
免疫原: | Fusion protein of human RASA4 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16939(RASA4 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [ |
シノニム: | RAS p21 protein activator 4 |
NCBI Summary: | This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O43374 |
NCBI GenInfo Identifier: | 299829175 |
NCBI Gene ID: | 10156 |
NCBI Accession: | NP_001073346 |
UniProt Related Accession: | O43374 |
Molecular Weight: | ~ 85, 90kDa |
NCBI Full Name: | ras GTPase-activating protein 4 isoform 2 |
NCBI Synonym Full Names: | RAS p21 protein activator 4 |
NCBI Official Symbol: | RASA4 |
NCBI Official Synonym Symbols: | GAPL; CAPRI |
NCBI Protein Information: | ras GTPase-activating protein 4 |
UniProt Protein Name: | Ras GTPase-activating protein 4 |
UniProt Synonym Protein Names: | Calcium-promoted Ras inactivator; Ras p21 protein activator 4; RasGAP-activating-like protein 2 |
Protein Family: | Ras GTPase-activating protein |
UniProt Gene Name: | RASA4 |
UniProt Entry Name: | RASL2_HUMAN |
Antibodies |
Anti-RASA4 Antibody (CAB9860) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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