RAB8B Antibody, Biotin conjugated (PACO38677)
- SKU:
- PACO38677
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | RAB8B Antibody, Biotin conjugated (PACO38677) |
抗体コード: | PACO38677 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Ras-related protein Rab-8B protein (15-204AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells. |
シノニム: | Ras-related protein Rab-8B, RAB8B |
UniProt Protein Function: | RAB8B: May be involved in vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells. Belongs to the small GTPase superfamily. Rab family. |
UniProt Protein Details: | Protein type:G protein, monomeric; Motility/polarity/chemotaxis; G protein, monomeric, Rab; G protein Chromosomal Location of Human Ortholog: 15q22.2 Cellular Component: peroxisomal membrane; phagocytic vesicle Molecular Function:GDP binding; protein binding; receptor binding Biological Process: antigen processing and presentation; cilium biogenesis; protein import into peroxisome membrane; protein secretion; vesicle docking during exocytosis |
NCBI Summary: | RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010] |
UniProt Code: | Q92930 |
NCBI GenInfo Identifier: | 13638434 |
NCBI Gene ID: | 51762 |
NCBI Accession: | Q92930.2 |
UniProt Secondary Accession: | Q92930,Q5JPC4, Q9P293, |
UniProt Related Accession: | Q92930 |
Molecular Weight: | 23,584 Da |
NCBI Full Name: | Ras-related protein Rab-8B |
NCBI Synonym Full Names: | RAB8B, member RAS oncogene family |
NCBI Official Symbol: | RAB8B |
NCBI Protein Information: | ras-related protein Rab-8B |
UniProt Protein Name: | Ras-related protein Rab-8B |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAB8B |
UniProt Entry Name: | RAB8B_HUMAN |