RAB4A Antibody (PACO42940)
- SKU:
- PACO42940
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RAB4A Antibody (PACO42940) |
抗体コード: | PACO42940 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Ras-related protein Rab-4A protein (1-218AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: Ras-related protein Rab-4A antibody at 2µg/ml + Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 24 kDa. Observed band size: 24 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO42940 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO42940 at dilution of 1:100. |
バックグラウンド: | Protein transport. Probably involved in vesicular traffic. |
シノニム: | Ras-related protein Rab-4A, RAB4A, RAB4 |
UniProt Protein Function: | Rab4: a member of the RAB family of RAS-related GTP-binding proteins, important regulators of vesicular transport and are located in specific intracellular compartments. RAB7 has been localized to late endosomes and shown to be important in the late endocytic pathway. In addition, it has been shown to have a fundamental role in the cellular vacuolation induced by the cytotoxin VacA of Helicobacter pylori. Mutations in this protein cause Charcot-Marie-Tooth type 2B neuropathy. |
UniProt Protein Details: | Protein type:G protein, monomeric; G protein, monomeric, Rab; G protein Chromosomal Location of Human Ortholog: 1q42-q43 Cellular Component: membrane; perinuclear region of cytoplasm; vesicle; endosome Molecular Function:GTPase activity; protein binding; GDP binding; GTP binding; protein transporter activity Biological Process: antigen processing and presentation; intracellular protein transport; metabolic process; regulation of endocytosis; Rab protein signal transduction |
NCBI Summary: | This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012] |
UniProt Code: | P20338 |
NCBI GenInfo Identifier: | 460018296 |
NCBI Gene ID: | 5867 |
NCBI Accession: | P20338.3 |
UniProt Secondary Accession: | P20338,Q5T7P7, Q9BQ44, |
UniProt Related Accession: | P20338 |
Molecular Weight: | 213 |
NCBI Full Name: | Ras-related protein Rab-4A |
NCBI Synonym Full Names: | RAB4A, member RAS oncogene family |
NCBI Official Symbol: | RAB4A |
NCBI Official Synonym Symbols: | RAB4; HRES1; HRES-1; HRES-1/RAB4 |
NCBI Protein Information: | ras-related protein Rab-4A; HTLV-1 related endogenous sequence |
UniProt Protein Name: | Ras-related protein Rab-4A |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAB4A |
UniProt Entry Name: | RAB4A_HUMAN |
Antibodies |
Anti-RAB4A Antibody (CAB13540) |
Anti-RAB4A Antibody (CAB6712) |
Anti-RAB4A Antibody (CAB3979) |
RAB4A Antibody (PACO11665) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |