RAB39B Antibody, FITC conjugated (PACO38132)
- SKU:
- PACO38132
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | RAB39B Antibody, FITC conjugated (PACO38132) |
抗体コード: | PACO38132 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Ras-related protein Rab-39B protein (1-213AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | May be involved in vesicular trafficking. Plays a role in synapse formation. May regulate the homeostasis of SNCA/alpha-synuclein. Together with PICK1 proposed to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR compostion at the post-synapses and thus synaptic transmission. |
シノニム: | Ras-related protein Rab-39B, RAB39B |
UniProt Protein Function: | RAB39B: May be involved in vesicular trafficking. Plays a role in synapse formation. Defects in RAB39B are the cause of mental retardation X- linked type 72 (MRX72). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. MRX72 patients can manifest autism spectrum disorder, seizures and macrocephaly as additional features. Belongs to the small GTPase superfamily. Rab family. |
UniProt Protein Details: | Protein type:G protein, monomeric, Rab; G protein, monomeric; G protein Chromosomal Location of Human Ortholog: Xq28 Cellular Component: Golgi apparatus; intracellular; neuron projection; vesicle Molecular Function:myosin V binding; protein binding Biological Process: synapse organization and biogenesis; vesicle-mediated transport Disease: Mental Retardation, X-linked 72 |
NCBI Summary: | This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. Mutations in this gene are associated with X-linked mental retardation. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q96DA2 |
NCBI GenInfo Identifier: | 27734447 |
NCBI Gene ID: | 116442 |
NCBI Accession: | Q96DA2.1 |
UniProt Secondary Accession: | Q96DA2,Q5JT79, Q8NEX3, |
UniProt Related Accession: | Q96DA2 |
Molecular Weight: | 24,622 Da |
NCBI Full Name: | Ras-related protein Rab-39B |
NCBI Synonym Full Names: | RAB39B, member RAS oncogene family |
NCBI Official Symbol: | RAB39B |
NCBI Official Synonym Symbols: | WSMN; MRX72 |
NCBI Protein Information: | ras-related protein Rab-39B |
UniProt Protein Name: | Ras-related protein Rab-39B |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAB39B |
UniProt Entry Name: | RB39B_HUMAN |