RAB35 Antibody (PACO01384)
- SKU:
- PACO01384
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RAB35 Antibody |
抗体コード: | PACO01384 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from the Internal region of human Rab 35. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | RAB35; RAB1C; RAY; Ras-related protein Rab-35; GTP-binding protein RAY; Ras-related protein Rab-1C |
UniProt Protein Function: | RAB35: In the process of endocytosis, essential rate-limiting regulator of a fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. Interacts with DENND1A and DENND1B in a nucleotide- dependent manner. The low binding to DENND1C is nucleotide- independent. All 3 DENND1 act as GEFs for RAB35 and thus activate the protein. Belongs to the small GTPase superfamily. Rab family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:G protein; G protein, monomeric, Rab; G protein, monomeric Chromosomal Location of Human Ortholog: 12q24.31 Cellular Component: cell projection membrane; clathrin-coated endocytic vesicle; coated pit; endoplasmic reticulum membrane; endosome membrane; Golgi membrane; intercellular bridge; plasma membrane Molecular Function:GDP binding; GTP binding; GTPase activity; phosphatidylinositol-4,5-bisphosphate binding; protein binding Biological Process: antigen processing and presentation; cytokinesis; endocytic recycling; endosome transport; ER to Golgi vesicle-mediated transport; neurite development; plasma membrane to endosome transport; protein localization |
UniProt Code: | Q15286 |
NCBI GenInfo Identifier: | 3024525 |
NCBI Gene ID: | 11021 |
NCBI Accession: | Q15286.1 |
UniProt Secondary Accession: | Q15286,B2R6E0, B4E390, |
UniProt Related Accession: | Q15286 |
Molecular Weight: | 17,058 Da |
NCBI Full Name: | Ras-related protein Rab-35 |
NCBI Synonym Full Names: | RAB35, member RAS oncogene family |
NCBI Official Symbol: | RAB35 |
NCBI Official Synonym Symbols: | RAY; H-ray; RAB1C |
NCBI Protein Information: | ras-related protein Rab-35 |
UniProt Protein Name: | Ras-related protein Rab-35 |
UniProt Synonym Protein Names: | GTP-binding protein RAY; Ras-related protein Rab-1C |
Protein Family: | Ras-related protein |
UniProt Gene Name: | RAB35 |
UniProt Entry Name: | RAB35_HUMAN |